Cardiology platform Chamber raises $60 million

Chamber Cardio announced a $60 million Series A round to support cardiologists and health plans in managing heart disease under value-based care models. The round was led by Frist Cressey Ventures, with participation from General Catalyst, AlleyCorp, American Family Ventures , Company Ventures, Optum Ventures, Healthworx Ventures, Black Opal Ventures, and debt financing from HSBC Innovation Banking.

The funding will be used to expand partnerships with health plans and cardiology practices, enter new markets, and grow the company’s clinical, operational, and technology teams.

Chamber partners with payers and cardiologists to support long-term cardiovascular care through a workflow-integrated platform that uses AI to identify high-risk patients, flag gaps in guideline-directed therapy, and reduce manual chart review. The company says its infrastructure is designed to help prevent complications and hospitalizations while giving health plans greater visibility into cardiovascular outcomes and total cost of care.

Cardiovascular disease remains the largest driver of healthcare spending in the U.S., with specialists often managing older, higher-risk patients without continuous data or support between visits, contributing to delayed interventions and avoidable utilization.

Chamber currently works with more than 500 cardiologists across seven states through multiple payer partnerships and plans to expand nationally.